Common complications of BM include pathological fracture, spinal compression, hypercalcemia and persistent pain. One important concept of BM treatment is called skeletal-related events SREswhich are defined as: a pathologic fracture, a spinal cord compression, a necessity for radiation to bone for pain or impending fracture or surgery to bone 4. If the patient presents with a luminal breast cancer with BM only, then sole endocrine therapy is reasonable for the start 8.
Secondary breast cancer is breast cancer that has spread from the breast to other parts of the body. Breast cancer starts as a lump in the breast - this is primary breast cancer. In many women, primary breast cancer does not come back after treatment.
Bone metastasis usually occurs in people who have been previously diagnosed with cancer or who have advanced cancer. But sometimes the pain of bone metastasis may be the first sign of cancer. But not all bone metastasis progresses rapidly. In some cases, it progresses more slowly and can be treated as a chronic condition that needs careful management.
Bone metastases are common in people who've had cancer, especially that of the breast, lung, or prostate. They occur when cells from the original tumor break off and take up residence in the bone. Metastases are very painful and are different from tumors that originate in the bone.
Your region is set as Change region. To help us to give you the most accurate information, please select the area of the UK you are from:. Secondaries in the bone are common with secondary breast cancer.
Imaging tests are used to investigate signs and symptoms that may indicate bone metastasis. Which tests you undergo depends on your specific situation. Treatments for bone metastasis include medications, radiation therapy and surgery.
The bones are the most common place where metastatic breast cancer cells tend to go. For more than half of women who develop stage IV breast cancer, the bones are the first site of metastasis. Although breast cancer can spread to any bone, the most common sites are the ribs, spine, pelvis, and long bones in the arms and legs. A sudden, noticeable new pain is the most common symptom of cancer that has spread to the bone.
Despite recent widespread patient screening advances as well as heightened health awareness, a significant proportion of women still present with advanced breast cancer. The diagnosis of a metastatic tumor suggests systemic treatment, along with local intervention targeting the primary tumor. Although there has been progress resulting from early detection and improved adjuvant therapy, the prognosis of breast cancer patients is still limited by the occurrence of distant metastases largely due to clinically occult micrometastases that remain undetected.
Metastatic breast cancer also called stage IV or advanced breast cancer is not a specific type of breast cancer. It's the most advanced stage of breast cancer. Metastatic breast cancer is breast cancer that has spread beyond the breast and nearby lymph nodes to other organs in the body most often the bones, lungs, liver or brain.